Highlights from last week in the Biosphere:
- AUBRAI trading volume has already generated over $167,000 in research funding for the lab of @aubreydegrey in its first 10 days live.Dr. de Grey hosted an X Spaces
- where he unveiled his vision for @Aubrai_, demonstrated live prompting and invited researchers to join the Aubrai training group.
- A proposal to fund Aubrai-assisted hypotheses passed Bio governance, inviting researchers to submit hypotheses for up to ~$25k in funding.
- A surge in the number of stakers led to BioXP upgrades, with last epoch's yapping XP expected to drop this coming week. Following this week's drop, XP distribution for yaps will occur very 3-4 days.
🌪 R&D Funnel of the Future
Aubrey co-hosted an X Spaces exploring the inner workings of Aubrai and discussing the potential of decentralized AI agents to create the R&D funnel of the future.
Highlights:
- For the first time, a leading scientist has a digital twin, giving the longevity community instant 24/7 access to Aubrey's knowledge as well as co-ownership of agent-generated IP.
- Aubrai is built on ElizaOS with a knowledge graph of 5k+ longevity papers, unpublished manuscripts and 45M open-access studies.
- Scientists can use Aubrai's chat (in private beta) to test ideas behind closed doors, while the public version on X stays open and transparent.
Aubrai/BioAgent Development
- The RMR2 Study is kicking off at Aubrey's lab (LEVF), streaming data and insights into the Aubrai agent.
- Aubrai Chat: invite now, token-gated next, mint IP-NFTs directly from the terminal.
- Attaching in-silico tools (e.g., AlphaFold-class, virtual cell models) with access tiers due to compute.
- Building scientific benchmarking to outperform general LLMs on domain tasks.
- Ongoing “cognitive engineering” to give agents heuristics/mental models for science; avoiding generic "agreeable” reasoning to support fringe, breakthrough thinking.
- Upcoming experiments with “backrooms” (multi-agent debates across disciplines) to spark cross-field insights.
- $250 in AUBRAI/USDC airdrops to longevity researchers with .edu emails who submit hypotheses to @Aubrai_, and up to $25k in funding for your experiment.
- Aubrai IPTs will be launched on Bio to fund additional experiments, with value flowing back to the Aubrai treasury.
- Next Ignition Sales TBA - work underway with BioDAOs and world-leading researchers.
🌐 Ecosystem Updates
- D1ckDAO created D-Age™ to assess men's reproductive aging powered by the BioAgent D1ckGPT, focusing on factors like hormonal balance, sperm count, sleep and more.
- Cerebrum DAO opened early access for Cerebrum Cortex, their brain health monitoring app.
- MicrobiomeDAO broke down their upcoming BioAgent, BiomeAI, and how it transforms microbiome health data into N=10 Trials and onchain assets, accelerating microbial discoveries. They also hosted a townhall, discussing their community growth, gut testing protocols and their roadmap.
- HairDAO is building the largest hair laboratory in the world, with 600 cryosections, 240 immunofluorescence stains and 55 follicles treated daily.
- Pump Science-backed compound Omipalisib onboarded Brian Kennedy, a leading aging researcher, as an advisor to explore its potential for superior lifespan extension compared to Rapamycin, with plans to launch three more compounds on Pump Science.
- ValleyDAO's FORGE project was highlighted by Molecule for its potential to turn e-waste into raw materials for AI, EVs and energy.
- PsyDAO's BeeARD project proposed a novel hypothesis on using vasopressin nasal spray to enhance psilocybin's therapeutic effects.
- Spectruth DAO is developing wearable devices to monitor vital signs, serving as an early warning system for PTSD symptoms.
- AthenaDAO hosted ReproTech sessions at Infinita City in Honduras, focusing on the future of fertility & reproductive longevity.
- Quantum Biology DAO cofounder @ClariceDAiello will speak tomorrow (Sept 8) at an event co-hosted by John Hopkins University on Quantum Computing transforming healthcare. Quantum Biology Institute is hiring a CEO.
Bio Community Updates
- We hosted a Bio Open Lab X Spaces discussing BioXP updates & the next BioAgents.
- Bio Asia tour: Paul Kohlhaas will speak at DeSci Seoul followed by a bio/acc rave in Seoul. In addition, Bio is hosting DeSci Summit Singapore around Token2049.
- $BIO was one of the top swapped tokens on Uniswap.
- DeSci Lisbon will take place on September 18, hosted by Bio, Cerebrum DAO, MicrobiomeDAO, PsyDAO, AxonDAO & Elata.
- Decentralized AI Researcher @S4mmyEth discussed the promise of BioAgents.
- The first DeSci Turkiye event was hosted at Builders Week Instanbul.
- The full @DeSciPilled episode with Bio CSO & co-founder James Sinka dropped on X.
- Dr. de Grey discussed why OpenAI's recent discovery signals a turning point in AI-powered biomedicine.
🧪 Explore DeSci projects on the Bio App

Stay updated via our Telegram, Discord & Governance forum. Follow @BioProtocolEco on X for real-time ecosystem updates.



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