Bio / Bio Monthly (May 2025): BioAgents, Small Molecules, Bio x AI Hackathon Prize, DeSci Knowledge Graphs

EcosystemJune 2, 2025

Bio Monthly (May 2025): BioAgents, Small Molecules, Bio x AI Hackathon Prize, DeSci Knowledge Graphs

Highlights from May in the Bio Ecosystem include midpoint winners of the Bio X AI Hackathon, integration of BioAgents into the Bio Launchpad and scientific updates at VitaDAO, CerebrumDAO and Long COVID Labs.

By Bio Community

Bio Monthly (May 2025): BioAgents, Small Molecules, Bio x AI Hackathon Prize, DeSci Knowledge Graphs

Highlights from the past month of bio acceleration:

The Bio x AI Hackathon crossed its midpoint, with $25K awarded in midpoint prizes, as part of the $125K total prize pool, to three teams, utilizing technologies from elizaOS, OriginTrail, and PrimeIntellect. The hackathon still offers $100K in remaining prizes. Submit a project in the Bio Discord by June 8, with winners being announced June 10 live at DeSci Berlin.
Bio co-founder Paul Kohlhaas shared a high-level vision for integrating AI scientists into the Bio Protocol, giving BioDAOs, pharma companies, and the general public new ways to interact with scientific ideas and experiments.
MycoDAO and SpineDAO crossed their funding thresholds and achieved successful public market debuts, with product development underway as well as incentivized data collection to generate decentralized knowledge graphs.
The Bio Core Team's 1-Year Cliff for BIO tokens, originally set to unlock on May 28 2025, will stay locked with the unlock pushed back six months, until November 2025.
Renowned MIT Professor Ed Boyden will join DeSci Berlin this month.

VitaDAO announced a call for projects for VitaLabs Season 2, inviting researchers to apply for funding to tackle high-risk longevity research over 4-month seasons -- Apply now. In addition, several VitaDAO-backed projects reported scientific updates, including VITA-FAST, VitaRNA, Rubedo Life Sciences, Repair Biotechnologies, and Cyclarity Therapeutics.
Cerebrum DAO's SK-Channels project was approved by the community to develop a small molecule drug targeting SK channels to treat ataxia and related tremors. They also shared a progress report highlighting their decentralized, double-blind, placebo-controlled trial for memory support, funding for 6 ventures, and partnerships with institutions like Harvard and Yale.
Long COVID Labs Patient #1 case study showed an 80% reduction in brain fog, 50–70% improvement in sleep and inflammation, but worsened post-exertional malaise and POTS symptoms, returning to baseline by day 30. LCL discussed its plans to build an open-source patient registry aggregating anonymized data on symptoms, treatments, and biomarkers, with data contributors receiving COVID tokens in return. Learn more.
Curetopia and Perlara are collaborating on a $580,000, 16–20 week project to screen drugs for 10 ARS gene mutations, having screened 96 drugs, identified 3 potential hits for secondary screening and validation, with potential NARS1 expansion. Learn more and watch their first livestream lab meeting.
ValleyDAO secured $100K in funding from leading climate biotech VC, JuniperVC to accelerate current projects and seed new SynBio projects. They also introduced their new AI co-pilot, ARI, enhancing research projects by aiding in idea transformation,with knowledge graph integration coming next. They also completed a 12-liter scale-up of their cocoa lipid fermentation, and their portfolio company BioHalo came out of stealth. Learn more.
PsyDAO's BeeARD project created a Psychedelic Science Knowledge Graph to generate hypotheses and identify overlooked scientific connections. They also launched the beta of their gamified platform, GraphSurfer, an AI-driven gamified platform facilitating learning in psychedelics and biomedicine through play to learn. Their novel ethnobotanical, Kéné Wasté, is also gaining early traction with early users reporting enthusiastic reviews like LSD-like hallucinations.
Nootropics DAO unveiled Nexus, an AI-powered research engine utilizing decentralized nootropics data to facilitate drug discovery & community-driven research through token incentives.
Quantum Biology DAO used their hypomagnetic chamber to study E. coli, extracting 40 micrograms of RNA for sequencing to explore magnetic field effects on gene expression. They are also creating a sensor dashboard to broadcast real-time lab conditions and results.
MicrobiomeDAO was announced as a new BioDAO, addressing the microbiome by leveraging prediction markets and decentralized data ownership, including initiatives like BiomeBanking. Learn more.
Pump Science did the first "F1y Grand Prix" at the Solana DeSci fair, offering participants a chance to win 2 million GOSSY and 800K ART tokens, using fruit flies to test performance-enhancing compounds. They’re soon launching 17 new compounds, with airdrops of each new token for RIF and URO holders.
HairDAO sectioned 1,680 hair follicle units and will investigate the effects of Olanzapine and Farnesol on them. They also launched their "Au Naturale," product on Anagen, a no-prescription hair regrowth product using natural ingredients to support scalp health and hair regrowth. The DAO also released a data packet, providing preclinical and in vivo observational studies on T3 and T4 thyroid hormones' impact on hair regrowth. Get exclusive access.
AthenaDAO launched a Fertility Acceleration site to track and trade fertility research projects and published their "Data & Wearables Report," exploring solutions to the scarcity of quality data in women’s health by leveraging AI, & more. They are also hosting a Demo Day on June 25, featuring 7 projects in ReproTech, Menopause, and AI for Fertility, plus new clinical research programs. Apply to attend.
CryoDAO is launching the American Biostasis Foundation to establish a leading cryopreservation facility for humans and pets.