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Bio Season 2: Building the Future of Permissionless DeSci

DeSci
Tech
Contents

It’s time for Bio to evolve from a curated launchpad into a factory for decentralized biotech. A system where builders move fast, conviction is rewarded, and frontier research can scale without permission.

Season 1 of the Bio Launchpad generated a wealth of data and learnings across our first project launches. Over 8,000 participants funded innovations in stem cell research, men’s health, psychedelic science & more.

But despite the traction, it quickly became clear that Season 1 was not designed for scale or sustainability.

  • Mercenary capital rotated from one sale to another, dumping their allocations post launch.
  • Pairing project tokens with BIO out of the gate tied network stability to volatile new assets.
  • BioXP incentives skewed too heavily toward short-term participants, reducing the incentive to hold and stake $BIO, the lifeblood of the system.
  • Research funding from trading fees didn’t meet the fundraising needs of biotech founders, undermining efforts to attract world-leading builders.

We realized if we want Bio to truly change how science gets built and funded globally, we needed a new model. One that attracts the best builders, removes friction and sustainably rewards conviction.

Enter Bio Season 2 - engineered to launch and grow a new generation of billion-dollar biotechs.

Key Upgrades:

  • ASSET/USDC pools: New tokens are paired in pools with USDC, not BIO; BIO/Asset pools are only added for successful projects that hit and sustain a target FDV.
  • More XP for BIO stakers: We’ve implemented a formula that heavily rewards veBIO (locked BIO) - effectively giving BIO stakers a larger share of XP, especially as more ecosystem tokens are staked.
  • Ecosystem Airdrops: Every new project will airdrop a percentage of its token supply to BIO stakers as a form of passive yield. (Planned to launch after the first wave of Season 2.)
  • Limit-Sell Fundraising: Projects only unlock funding as they achieve market traction. Token sales are automatically executed via limit orders once a project’s FDV remains above preset thresholds, aligning fundraising with real growth.
  • Instant BioXP: Users who need BioXP on short notice will be able to stake and lock BIO to get XP instantly, minus a fast track fee. This provides immediate access to ongoing sales while still locking up BIO. (Planned to launch after the first wave of Season 2.)
  • Aerodrome Pools: All new tokens will launch their liquidity on Aerodrome (via USDC pools), enabling eligible assets to be tradeable on Coinbase from day one.
  • x402 x BioAgents: We’re open-sourcing the BioAgents framework and integrating it with Coinbase’s x402 payments protocol. This will allow DeSci agents to transact seamlessly with each other and with humans, powering onchain agentic commerce across research and health use-cases.
  • BNB Chain Bridge: The BIO token is being bridged to the BNB Chain, extending Bio’s reach into the BNB ecosystem and paving the way for other ecosystem assets to be bridged as well.

The upgraded BioXP formula for BIO stakers will be pushed live in the coming days – meaning going forward, the system will heavily favor BIO stakers.

Stake BIO now to start accumulating BioXP for access to the 1st wave of Season 2 Sales.

Below we'll dive deeper into the design of Bio S2.

I. Launch & Early Trading

USDC/ASSET Pools

  • After a successful Ignition Sale, newly launched tokens will be paired in an AMM with USDC, instead of BIO. By adding USDC for initial liquidity, we remove the risk of an under-performing token dragging down BIO’s price.
  • Successful assets get an ASSET/BIO only once they sustain above a pre-set FDV.
  • This design also allows for tokens to be launched permissionlessly on Bio with ASSET/USDC pools, while shielding BIO holders during a project’s most volatile early days.

The result: more assets, more shots on goal to drive value back to the network.

Ecosystem Airdrops

  • Every Ignition Sale distributes a percentage of the token’s initial supply to BIO stakers, creating a passive form of yield for BIO stakers.
  • Note: Ecosystem airdrops are slated to go live after the first wave of S2 launches.

Aerodrome Pool Launcher

  • Following a successful Ignition Sale, new tokens on Bio will launch their liquidity on Aerodrome, via a ASSET/USDC pool.
  • Through this integration, any eligible token that launches on Bio will trade on Coinbase on day one.
  • By tapping into Aerodrome’s platform, projects gain instant exposure to Coinbase’s vast user-base, expanding accessibility and liquidity.

II. Tokenomics & Fundraising

Limit-Sell Fundraising

  • Bio Season 2 introduces a limit-sell fundraising mechanism to align funding with project traction.
  • Instead of raising a lump sum upfront or relying solely on trading fees, 5% of each project’s token supply is reserved to be sold gradually as the project’s market value grows.
  • The sales will be made via transparent DEX limit orders once the project’s valuation remains above certain FDV thresholds and will continue to sell incrementally at higher valuation milestones.

The result: Project teams receive proceeds only when real market traction occurs, aligning incentives between projects and their holders.

Vesting

  • To encourage stability post-launch, Ignition Sale participants get 20% of their tokens liquid at TGE, while the remaining 80% vests linearly over the next 30 days.
  • By aligning everyone through a brief vesting period, Season 2 aims to create a more stable early market and discourages quick-flip behavior.

III. BioXP

BIO Staking Rewards Increase

  • Staking BIO now yields a much larger share of BioXP compared to staking ecosystem tokens and other ecosystem activities.
  • Moreover, a portion of the total amount of XP generated by ecosystem staking and other activities (BIO staking excluded) is redistributed pro rata to BIO stakers. In other words, the more ecosystem tokens that are staked across Bio, the more bonus XP BIO stakers collectively earn. This aligns the whole network’s activity with rewards for BIO holders.

Flexible Multipliers for Ecosystem Token Staking

  • Each ecosystem token can have its XP reward multiplier adjusted individually.
  • This lets the Bio community boost incentives for staking certain tokens - for instance, in a new token’s early days post-launch to bootstrap growth.

Increased Max  Allocation

  • To accommodate stronger conviction and larger capital allocators, users can now purchase up to 1% of a token’s initial supply during its Ignition Sale, up from the previous 0.5% max per user allocation in Season 1.
  • This upgrade brings deeper liquidity and commitment from larger backers at the token’s inception.

Instant BioXP

  • What if you discover a live Ignition Sale late and don’t have the BioXP to participate? Season 2 introduces Instant BioXP to solve this.
  • Users can stake BIO, and lock it for a period of time to instantly receive the XP for that timeframe minus a fast track fee.
  • For example, suppose locking a given amount of BIO for two weeks would normally earn you 100 XP by the end; with Instant BioXP, you might lock that BIO and get, say, 60 XP immediately to use in the ongoing sale.
  • This feature gives newcomers a way to jump into a sale immediately while still bolstering long-term BIO staking.
  • Note: Instant BioXP is planned to go live after the first wave of Season 2 launches.

IV. Other Changes

x402 x BioAgents

  • We’re releasing a new open-source version of the BioAgents framework that’s compatible with Coinbase’s x402 payment protocol.
  • This means autonomous science agents in the Bio ecosystem will be able to transact via x402, whether it’s agent-to-agent or agent-to-human payments.
  • A BioAgent could autonomously pay for services or datasets, or sell its analytical outputs, all using onchain x402 transactions.

This integration paves the way for a new era of agent-driven commerce in research and health, where BioAgents can seamlessly exchange value and services.

Binance Smart Chain Bridge

  • We are building a bridge to connect BIO to Binance Smart Chain, allowing BIO to move into Binance’s ecosystem.
  • This creates an entry point for BSC users and liquidity to flow into Bio, and vice versa.
  • In time, we’ll also establish pathways for other Bio ecosystem tokens to bridge to BSC.

Season 2 is how Bio scales DeSci to the world.

Science should be open. Capital should be agile. Access should be earned.

Stake BIO now to stack BioXP and be ready for the first wave of Season 2 Sales. Coming soon!
https://www.bio.xyz/blog-posts/bio-season-2-building-the-future-of-permissionless-desci